Receptor Gene Databases ======================= Receptor gene databases are essential for understanding cell communication networks. ReCoN provides pre-compiled receptor gene lists for human and mouse, derived from NicheNet's prior knowledge network (PKN). These databases are used to identify receptor-ligand interactions in single-cell RNA-seq data. Available Databases ------------------- - **Human Receptor Genes**: Derived from NicheNet's PKN. - **Mouse Receptor Genes**: Derived from NicheNet's PKN. Usage ----- To load receptor gene databases in ReCoN, use the `load_receptor_genes` function: .. code-block:: python from recon.data import load_receptor_genes # Load human receptor genes human_receptors = load_receptor_genes("human_receptor_gene_from_NichenetPKN") # Load mouse receptor genes mouse_receptors = load_receptor_genes("mouse_receptor_gene_from_NichenetPKN") These functions return a pandas DataFrame containing receptor gene information. Integration in Tutorials ------------------------- Receptor gene databases are used in the following tutorials: 1. **Predicting Treatment Effects**: Identifying receptor-ligand interactions. 2. **Building GRNs with HuMMuS**: Using receptor genes to infer gene regulatory networks. For more details, refer to the respective tutorials in the documentation.